Topics

1.	Value Generation in Biopharmaceutical Industry
	- Molecular Methods Improving Protein Production (Protein Modification and Engineering) - Separation of Recombinant Proteins - Stationary Phases and Column Characteristics – Material Requirements - Platform Technologies for Process Development Abstract: The design, development and optimization of packings and stationary phases on analytical, preparative and process scale will be a central subject at the conference. A special session will be held organized by F. Svec and K.K. Unger to highlight novel types of stationary phases and to discuss their characterizatiion and properties with respect to value generation in biopharmaceuticals.

2.	Biorecognition: Exploiting Selective Interactions of Biomolecules
	- Selectivity, Specificity, Affinity - Ligand Selection, Surface Phenomena, Biosensors - Functional Information from Separation Behaviour Abstract: The enrichment of low-abundance molecules is critical for their detection, identification and quantification. The session on Exploiting Selective Interactions of Biomolecules will focus on recent developments in the areas of affinity ligand development and affinity chromatography. This session links closely to the areas of proteomics and immunochemistry.

3.	Fundamentals in Chromatographic and Electrochromatographic Separations
	- Interphase Equilibria and Mass Transport - Ion Exchange and Hydrophobic Interaction Abstract: The session deals with the basic mechanisms of separations and their parameters which establish the separation process (phase equilibria) and efficiency (kinetics and mass transport) with special emphasis on biopurification and bioanalysis.

4.	Detection and Separation Methods Supporting Protein/Polynucleotide Analysis
	- Multidimensional Separation Methods - Protein Conformation and Protein Stability - Characterisation of Plasmids / Viruses for Therapeutic Applications - Detection of Posttranslational Modifications - Automation and Data Handling - Bioinformatics - Data Handling and Analysis

5.	Advances of Bioprocessing Operations
	- Chromatographic Reactors, Expanded Bed Adsorption, Magnetic Beads, SMB for Biopharmaceuticals - PAT-Initiative, Qualification, Quantification - Processes and Equipment Abstract: Chromatographic separations play an important role in separation and processing of recombinant proteins, therapeutic plasmids and became an interesting option even in the separation of viruses and other biological nanoparticles. The selectivity of chromatographic separations is highest among all separation methods. The process can be conducted in aqueous electrolyte solutions with high recovery of biologically active products and high productivity. The session includes progress in thermodynamics of adsorption of biomolecules, mass transfer, kinetics, and novel stationary phases and examples of applications of chromatographic and related methods for purification of peptides, proteins and polynucleotides.