Programme

Thursday, October 14, 2010
09:00 - 09:15	Welcoming remarks and opening of the workshop U. Reichl, Max-Planck-Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany
1. General aspects of viral vaccine production
Session chairs:	Prof. Dr. Stefan Kochanek Prof. Dr. Manuel J.T. Carrondo
09:15 - 09:45	Future issues in viral vaccine development and manufacturing G. Auniņš, Merck Research Laboratories, North Wales, PA, USA
09:45 - 10:15	Trends and challenges in process development for new viral vaccines A. Neubert, IDT Biologika GmbH, Dessau-Rosslau, Germany
10:15 - 10:45	Coffee break
10:45 - 11:00	Issues in production of viral gene transfer vectors S. Kochanek, University of Ulm, Germany
11:00 - 11:30	Efficient chemically-defined production processes with the AGE1.CR duck cell line I. Jordan, V. Sandig, ProBioGen AG, Berlin, Germany
11:30 - 12:00	Registration pathway of novel vaccines H. Meyer, Paul-Ehrlich-Institut, Langen, Germany
12:00 - 13:00	Round table discussion
13:00 - 14:00	Lunch
2. Specific aspects of viral vaccine production
Session chairs:	Dr. Leo van der Pol Prof. Dr.-Ing. Udo Reichl
14:00 - 14:30	Production of retroviral vectors for gene therapy K. Kühlcke, EUFETS GmbH, Idar-Oberstein, Germany
14:30 - 14:50	Inactivated Polio Vaccine (IPV) production using attenuated sabin strains as an example of future viral vaccine development W.A.M. Bakker, Y.E. Thomassen, A.G. van 't Oever, J. Westdijk, M.G.C.T. van Oijen, P. van 't Veld, L. Sundermann, G.F.A. Kersten, J. van der Gun, A. Hamidi, N. van den Heuvel, L.A. van der Pol, Netherlands Vaccine Institute, Bilthoven, The Netherlands
14:50 - 15:10	Improving baculovirus production at high cell density through manipulation of energy metabolism P.M. Alves, ITQB / IBET, Oeiras, Portugal
15:10 - 15:30	The challenge to produce vaccines of high quality - cultivation of kidney-derived animal cell lines in minimal culture media F. Messi, Cell Culture Technologies LLC, Gravesano, Switzerland
15:30 - 16:00	Coffee break
16:00 - 16:30	Quality by design for viral vaccine production L. van der Pol, Netherlands Vaccine Institute, Bilthoven, The Netherlands
16:30 - 17:00	New assay platforms U. Reichl, Max-Planck-Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany
17:00 - 17:20	High throughput microchip capillary gel electrophoresis protein process development C. Salomo, Caliper Life Sciences GmbH, Mainz, Germany
17:20 - 17:40	Glycosylation pattern analysis of viral antigens E. Rapp, Max-Planck-Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany
17:40 - 18:00	Round table discussion
19:00	Dinner at the "Vinum" Kleine Hochstr. 9, 60313 Frankfurt am Main

Friday, October 15, 2010
3. Downstream processing of viral vaccines
Session chairs:	Prof. Dr. Manuel J.T. Carrondo Prof. Dr.-Ing. Udo Reichl
09:00 - 09:30	Viral vaccine processes: towards intensification and quality M. de Vocht, Crucell Holland BV, Leiden, The Netherlands
09:30 - 10:00	Challenges in the development and production of live virus vaccines R. Morenweiser, GE Healthcare Europe GmbH, Munich, Germany
10:00 - 10:20	Next generation technologies of vaccine production using novel separation platforms A. Strancar, BIA Separations d.o.o., Ljubljana,Slovenia
10:20 - 10:50	Coffee break
10:50 - 11:10	Challenges in downstream processing of viral vaccines M.J.T. Carrondo, IBET, Oeiras, Portugal
11:10 - 11:30	Virus purification with membrane chromatography S. Fischer-Fruehholz, L. Chirica, M. Hirai, R. Faber, U. Gottschalk, Sartorius Stedim Biotech GmbH, Göttingen, Germany
11:30 - 11:50	Downstream processing of cell culture-derived influenza virus M. Wolff, Max-Planck-Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany
11:50 - 13:00	Round table discussion and wrap-up meeting