Updated Programme of Nov. 9

Programme for download (2 MB). Please save the file on your computer.

	Tuesday, November 15, 2011
09:00	Registration
10:00	Welcome and Opening
	IGM - BASIC SCIENCE, ISOLATION
10:15	Characterization of IgM-antigen interactions using fluorescence detection in the analytical ultracentrifuge
	Y.-F. Mok, Z. Rosenes, T.D. Mulhern, D.M. Hatters, G.J . Howlett, University of Melbourne, Parkville/AUS
10:45	Generation of different IgM glycoforms in plants
	A. Loos, C. Gruber, University of Natural Resources and Life Sciences, Vienna/A; F. Hensel, Patrys GmbH, Würzburg/D; F. Altmann, H. Steinkellner, University of Natural Resources and Life Sciences, Vienna/A
11:15	Coffee Break
	UPSTREAM / DOWNSTREAM DEVELOPMENT
11:30	Oxidation-specific epitopes are major targets of natural IgM antibodies
	C. Binder, Medical University of Vienna/A
12:00	Purification and characterization of human recombinant IgMs
	R. Kunert, A. Mader, University of Natural Resources and Life Sciences, Vienna/A
12:30	Layered beads: new tool for IgM purification
	T.E. Söderman, GE Healthcare, Uppsala/S
13:00	Lunch, followed by coffee break and exhibition
14:30	A two-step workflow for the purification of monoclonal IgM
	X. He, J . Liao, R. Frost, Bio-Rad Laboratories, Inc., Hercules, CA/USA
15:00	The quest for a broadly applicable IgM purification platform
	P. Gagnon, J . Lee, M. Van Beers, Bioprocessing Technology Institute, Singapore/SGP
15:30	Coffee Break
16:00	Automated platform for purification of autologous human IgM
	J . Jorgensen, C.S. Santos, S. Waniger, A.M. McCord, M.A. Popa, M. Hirschel, Biovest International, Minneapolis, MN/USA
16:30	Screening and quantification of human IgMs using BioLayer interferometry
	A. Mader, R. Kunert, University of Natural Resources and Life Sciences, Vienna/A
16:50 -17:10	Development of an affinity HPLC analytical method for the quantification of IgM with monolithic columns
	B. Gabor, P. Kramberger, T. Jakop, M. Barut, BIA Separations d.o.o., Ajdovšcina/SLO; F. Hensel, Patrys GmbH, Würzburg/D; A. Štrancar, BIA Separations d.o.o., Ajdovšcina/SLO
17:30	Get-Together - sponsored by

	Walk to the Tram Station "Festhalle/Messe" and enjoy a city sightseeing tour with the historic tram EBBELWEI Express (Apple Wine Express). Taste a glass of original Frankfurt apple wine or apple juice and a pretzel on board. After the tour relax and enjoy hospitality at an traditional pub "Zum Feuerrädchen" with typical Frankfurt style of cuisine. www.zum-feuerraedchen.de. A bus will take you back to Mercure hotel at approx. 22:30 h.
	Wednesday, November 16, 2011
	UPSTREAM / DOWNSTREAM DEVELOPMENT
09:00	CaptureSelect: one-step solution for IgM purification
	J. Schreffler, Morphotek Inc., Exton, PA/USA; F.J.M. Detmers, BAC B.V., Naarden/NL
09:30	Upstream & downstream challenges of clinical production of a human IgM antibody therapeutic
	M.E. Ultee, Laureate Biopharmaceutical Services, Inc., Princeton, NJ/USA
10:00	Lowering the production costs of IgM by using fast in-process HPLC and multiuse disposable columns
	M. Barut, M. Simic, A. Strancar, BIA Separations, Ljubljana/SLO
10:30	Coffee Break
	FORMULATION / CLINICAL DEVELOPMENT
11:00	Room for antibody patents in a crowded field
	G. Redl, REDL Life Science Patent Attorneys, Vienna/A
11:30	Stabilization of IgM monoclonal antibodies from cell culture through formulation
	M. Mueller, M. Loh, A.B. Choo, P. Gagnon, Agency for Science, Technology and Research, Singapore/SGP; A. Jungbauer, University of Natural Resources and Life Sciences, Vienna/A
12:00	Long time storage of IgM as liquid formulation - an overview
	M. Tarköy, M.P. Rudolf, Kenta Biotech AG, Bern/CH
12:30	Preliminary results from a first-in-human trial of PAT-SM6 IgM in patients with melanoma
	D. Greenwood, A. Hedt, Patrys Ltd, Melbourne/AUS; S. Brändlein, University of Wuerzburg/D; F. Hensel, Patrys Ltd, Melbourne/AUS
13:00	Lunch, followed by coffee break and exhibition
14:30	An integrated approach using IgM antibodies to eliminate residual pluripotent stem cells - improving the safety of stem cell therapy
	A.B.H. Choo, H.L. Tan, K. Schriebl, Bioprocessing Technology Institute, Singapore/SGP
15:00	Comparability of effector function of fully human IgM derived from hybridoma or recombinant CHO expression
	M.P. Rudolf, S. Fas, O. Rutschi, Kenta Biotech AG, Bern/CH
15:30	The natural IgM antibody SM-6 specifically targets and kills primary multiple myeloma cells by induction of apoptosis and complement activation
	L. Rasche, University Hospital Wuerzburg/D; F. Hensel, Patrys GmbH, Würzburg/D; S. Brändlein, University of Wuerzburg/D
16:00	A single institution phase I study of an IgM mAb with chemotherapy for the treatment of patients with relapsed or refractory B-lineage acute lymphoblastic leukemia M. Liedtke, C. Twist, M. Bieber, N. Bhat, S. Coutre, N. Teng, Stanford Cancer Center, CA/USA
16:30	End of the workshop