Lecture Programme

Tuesday, June 08, 2010

13:00	Opening H.W. Fuchs, O. Engelking, CellSystems® Biotechnologie Vertrieb GmbH, St. Katharinen/D

	*In Vitro Toxicity*
	Chair: H. Spielmann, Freie Universität Berlin/D

13:15	PLENARY LECTURE Successful validation and acceptance of RHE based methods of regulatory toxicity testing H. Spielmann, Freie Universität Berlin/D
14:00	The COLIPA program for animal-free genotoxicity testing - an overview R. Fautz, KPSS-Kao Professional Salon Services GmbH, Darmstadt/D; S. Pfuhler, The Procter & Gamble Co., Cincinnati, OH/USA; P. Carmichael, Unilever, Sharnbrook/UK; W. Diembeck, Beiersdorf AG, Hamburg/D; A. Lynch, GlaxoSmithKline UK Ltd., Ware/UK; N. Hewitt, Scientific Writing Services Erzhausen/D; A. Latil, Pierre Fabre, Toulouse/F; G. Ouedraogo, L'Oreal Life Sciences Research, Aulnay sous Bois/F; K. Reisinger, Henkel AG & Co KGaA, Düsseldorf/D; M. Marrec-Fairley, COLIPA, Brussels/B
14:20	Phototoxicity in vitro: investigation of photoreactions in the skin using the reconstructed epidermis "Epidermal Skin Test 1000" (EST 1000) J. Hoffmann, Advanced CellSystems GmbH, Troisdorf/D; E. Heisler, A. Thiemann, S. Weimans, Evonik Stockhausen GmbH, Krefeld/D; H.W. Fuchs, Advanced CellSystems GmbH, Troisdorf/D
14:40	Progress on the development of skin equivalent based assays to distinguish sensitizers from non sensitizers and to determine sensitizer potency K. Ouwehand, S.W. Spiekstra, G.G. dos Santos, R.J. Scheper, T.D. de Gruijl, S. Gibbs, VU University Medical Centre, Amsterdam/NL
15:00	Coffee break / Exhibition / Poster discussion

	*Functional Characteristics*
	Chair: B. de Wever, ALTEXA Development, Monaco/MC

16:00	Barrier properties of human skin equivalents J. Bouwstra, V.S. Thakoersing, G.S. Gooris, M. Rietveld, M. Ponec, Leiden University/NL; A. El Ghalbzouri, Leiden University Medical Center/NL
16:20	Development of a vascularised skin equivalent for adsorption testing F. Groeber, J. Hansmann, University of Stuttgart/D; M. Kaufmann, H. Walles, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart/D
16:40	Epidermal stem cell maintenance and endothelial vessel formation are regulated by both the mircoenvironment and cell-cell interactions in organotypic skin cultures in vitro. K. Boehnke, H.-J. Stark, S. Muffler, P. Boukamp, German Cancer Research Center, Heidelberg/D
17:00	What do we know from the COLIPA skin metabolism project about xenobiotic detoxification capacities of skin models? C. Götz, K. Ruwiedel, R. Pfeiffer, U. Hübenthal, J. Tigges, E. Fritsche, IUF gGmbH, Düsseldorf/D; R. Edwards, Imperial College, London/UK; P. Aeby, Procter & Gamble, Marly/CH; C. Goebel, Procter & Gamble, Darmstadt/D; C. Pease, Unilever, Bedford/UK; N. Hewitt, Scientific Writing Services, Erzhausen/D;
17:20	PLENARY LECTURE Delivering skin models to customers: an overview of 20 years entrepreneurship B. de Wever, ALTEXA Development, Monaco/MC
17:50	End of the first conference day
18:15 - 23:00	Shuttle / Conference Dinner

Wednesday, June 09, 2010

	*Disease Models*
	Chair: E. Tschachler, Medizinische Universität Wien/A

09:00	PLENARY LECTURE Three-dimensional models of normal and diseased human skin A. El Ghalbzouri, Leiden University Medical Center/NL
09:30	Induced expression of GLI1 or GLI2 suppresses differentiation in HaCaT 3D-cocultures H.A. Russ, German Cancer Research Center, Heidelberg/D;H. Schnidar, University of Salzburg/A; M. Angstmann, P. Boukamp, M.M. Mueller, German Cancer Research Center, Heidelberg/D; C. Maercker, Mannheim University of Applied Sciences/D; F. Aberger, University of Salzburg/A; D. Breitkreutz, German Cancer Research Center, Heidelberg/D
09:50	Identification of novel in vitro test systems for the determination of glucocorticoid receptor ligand induced skin atrophy S. Schoepe, H. Schäcke, Bayer Schering Pharma AG, Berlin/D; A. Bernd, N. Zöller, University of Frankfurt/D; K. Asadullah, Bayer Schering Pharma AG, Berlin/D
10:10	A human skin explant model - applications in research and clinical practice A. Dickinson, X.N. Wang, I.T. Scoular, Alcyomics Ltd, Newcastle upon Tyne/UK
10:30	*In vitro infection models of localized candida* infections** G. Weindl, Freie Universität Berlin/D
10:50	Coffee break / Exhibition / Poster discussion
11:35	Development and applicability of an in vitro wound healing model S. Küchler, N.B. Wolf, M. Schäfer-Korting, Freie Universität Berlin/D
11:55	De novo generated human hair follicle like microorganoids and their use in skin equivalents in vitro R. Horland, I. Wagner, R. Lauster, G. Lindner, TU Berlin/D
12:15	Monitoring of genomic response in reconstituted human 3D tisssues M. Meloni, B. De Servi, VitroScreen, Milan/IT
12:35	PLENARY LECTURE Gene silencing in a reconstructed human skin model M. Mildner, Medizinische Universität Wien/A
13:05	Lunch break / Exhibition / Poster discussion

	*Clinical Application*
	Chair: E. Tschachler, Medizinische Universität Wien/A

14:05	Clinical application of in vitro generated skin O. Rennekampff, Medizinische Hochule Hannover/D
14:25	Cell therapy of burns: present and future J.-J. Lataillade, Hôpital d'Instruction des Armées Percy,Clamart/F
14:45	Development of a 3D pigmented skin model to evaluate RNAi-induced depigmentation M. Van Gele, B. Geusens, J. Lambert, Ghent University/B
15:05	Closing Remarks H.W. Fuchs, O. Engelking, CellSystems® Biotechnologie Vertrieb GmbH, St. Katharinen/D

Programme subject to change