Trends in Metabolomics - Analytics and Applications

June 09, 2008 - June 10, 2008, DECHEMA-Haus, Frankfurt am Main/Germany

kopka

09 - 10 June 2008, DECHEMA-Haus, Frankfurt am Main

Ten years ago the term “Metabolomics”, which defines the entire metabolic content of a cell or organism at a given time point, was introduced to the scientific community. Monitoring results of qualitative and quantitative analysis of a high number of metabolites reflects the functional status of biological entities at the fundamental metabolic basis. During the last decade, metabolomics closed an important gap in the area of post genome research. Determining the information flow from genome to transcriptome, proteome and finally metabolome allows, for the first time, a comprehensive description of living systems. To establish models and data sets for a precise simulation and prediction of physiological properties of cells, however, in silico reconstructions of metabolic pathways and high performance empirical metabolomic studies technologies are essential. The next logical step in metabolomics is to link metabolite pool measurements with metabolic fluxes and gene regulation, to fully cover the dynamics of living systems. Beside the causal analysis of living systems, metabolomics is ideally suited to search for novel biomarkers in disease detection or in monitoring the success of pharmacological intervention. Further aspects of metabolomics range from biotechnology to environmental monitoring to food quality applications.

This first metabolomics meeting hosted by DECHEMA aims to cover trends ranging from technical developments in analytics, integration of metabolomics into systems biology to biomarker discovery in health, nutrition, and medical aspects.

Topics:

- Methods for Metabolomics

- Microbial Systems

- Plant Systems

- Animal- and Medicinal Relevant Systems

- Bioinformatics & Systems Biology